Message Number: SG14630 | New FHL Archives Search
From: sukiec@optonline.net
Date: 2002-02-02 22:24:00 UTC
Subject: Post mortem guidelines for ferret owners
To: ferrethealth@smartgroups.com
Message-ID: <7245975.1120797820182.JavaMail.root@thallium.smartgroups.com>

As to cost: you would need to ask your vet. Remember that pathology is also usually needed.

http://fhl.sonic-weasel.org/browse.php?msg=YG10682

provides essential information on guidelines for postmortems.

Since it hasn't appeared in a while I'm going to do a co-moderator-thing and include the text of a past post from Dr. Bruce Williams, who is a veterinary pathologist as well as being a ferret health expert, to help all since this is a topic it is best to know before it is needed:

START QUOTE


Mike reminded me of a post that I had placed on the FML a while back,
that may be of use to people who are faced with imminent demise of a
ferret for unknown reasons. It is not a recipe for doing your own
autopsy, but may will give you some general guidelines on how to
maximize the diagnostic information which you can
get from a post mortem. how to make sure if one is done, you get the
best return.

Many vets actually do not know much about doing
autopsies, so this information may be very important to you.

1. Have the post done as quickly as possible. From the moment of
death, a ferret's body begins to decompose. The different tissues decompose at
different rates, based on their composition. As a general rule, the
digestive system, by its very nature, decomposes fastest - you might
say it digests itself. The gall bladder which is filled with bile, a
digestive compound, goes first - usually within 2 hours. Between six and
twelve hours, the lining of the digestive tract, what I usually rely on to make a
diagnosis of ECE, is gone, due to the presence of bacteria, food, and
digestive enzymes. The pancreas, a storehouse of digestive enzymes,
also decomposes fast. Generally, if you have an undiagnosed digestive
disease and the tissues aren't in formalin within 12 hours, you have markedly
diminished your chances of making a diagnosis.

2. The end point of decomposition is when the tissues are placed in
formalin, or another fixative, by the vet. Formalin immediately
halts all decomposition by cross-linking proteins. What I see under the
microscope is a picture of the tissue when it hit the formalin.

3. Refrigeration slows decomposition, but does not stop it. Freezing
damages the tissues beyond all recognition under the microscope - all the
water in the cells is frozen into ice crystals, and when they are thawed, the
cells are destroyed. Never freeze tissues that are going to pathologists
for microscopic examination. Freezing is only for tissues to preserve
pathogens for later culture.

4. The ideal way to obtain a post mortem is immediately following
euthanasia. Have your vet block out time to euthanize and do the
post.

5. If you are doing a necropsy - take the widest range of tissues
possible - even tissues you don't think are involved. One of the most
frustrating things about being a pathologist is only getting two or three
tissues in an animals in which a disease was not diagnosed ante mortem. If you are
not sure what is going on, sample everything.

6. Don't due an "abdominal post" - sample the thoracic organs, as
well as a range of lymph nodes, eyes, and the nervous system.

7. If the animal is showing neurologic signs, it is very important
to submit brain and spinal cord.

8. Make sure to use 10 parts formalin to 1 part tissue for proper
fixation. Throwing a large lump of tissue into a small amount of formalin
delays fixation and allows the tissue to continue to decompose.

9. This is most important - if you don't post within 48 hours - you
probably have missed the window of opportunity. The amount of diagnostic
information that is lost after 48 hours probably will render an autopsy into a
frustrating and cost-ineffective exercise for the owner, veterinarian, and
pathologist.

10. Remember that animals die at the least opportune moment -
usually 5 minutes after the vet has closed the clinic for the weekend. If you
have a sick ferret that may not make it, and you want a necropsy done, make
your wishes known to your vet before the moment comes. They will more
likely be available after hours for you.

Just a couple of guidelines which may save you extra grief during at
a difficult time.

END QUOTE

One note to all: You never know how important it is to have options for emergencies that happen after hours or when your vet is away until you are actually in that situation. Try to figure out where to go and who to see beforehand.

-- Sukie (not a vet)
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